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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP3K11
All Species:
21.52
Human Site:
T458
Identified Species:
47.33
UniProt:
Q16584
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16584
NP_002410.1
847
92688
T458
E
V
F
E
R
E
L
T
L
L
L
Q
Q
V
D
Chimpanzee
Pan troglodytes
XP_508556
847
92664
T458
E
V
F
E
R
E
L
T
L
L
L
Q
Q
V
D
Rhesus Macaque
Macaca mulatta
XP_001113486
847
92847
T458
E
V
F
E
R
E
L
T
L
L
L
Q
Q
V
D
Dog
Lupus familis
XP_540853
722
79730
P363
A
D
C
W
A
Q
D
P
H
R
R
P
D
F
A
Cat
Felis silvestris
Mouse
Mus musculus
Q80XI6
850
93208
T459
E
V
F
E
R
E
L
T
L
L
L
Q
Q
V
D
Rat
Rattus norvegicus
Q66HA1
850
93091
T459
E
V
F
E
R
E
L
T
L
L
L
Q
Q
V
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q7T2V3
1005
111856
D452
E
L
A
E
R
E
I
D
I
V
E
R
E
L
N
Zebra Danio
Brachydanio rerio
XP_690016
976
108571
N459
Q
L
A
E
R
E
I
N
V
L
E
R
E
L
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q95UN8
1161
128942
E472
E
Q
N
L
R
E
R
E
R
V
L
I
E
R
E
Honey Bee
Apis mellifera
XP_395037
1102
123539
T539
D
L
L
E
R
E
L
T
V
M
I
I
Q
Q
Q
Nematode Worm
Caenorhab. elegans
O01700
928
103465
K450
N
M
Y
E
M
K
L
K
R
T
N
K
M
Y
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.3
82.6
N.A.
94.4
93.8
N.A.
N.A.
N.A.
43.3
46.5
N.A.
30.3
35.6
20.6
N.A.
Protein Similarity:
100
99.6
98.8
83.7
N.A.
95.4
95.4
N.A.
N.A.
N.A.
56.6
58.7
N.A.
43.8
49.2
35.7
N.A.
P-Site Identity:
100
100
100
0
N.A.
100
100
N.A.
N.A.
N.A.
26.6
26.6
N.A.
26.6
40
20
N.A.
P-Site Similarity:
100
100
100
6.6
N.A.
100
100
N.A.
N.A.
N.A.
80
80
N.A.
46.6
73.3
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
19
0
10
0
0
0
0
0
0
0
0
0
10
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
0
0
0
0
10
10
0
0
0
0
10
0
55
% D
% Glu:
64
0
0
82
0
82
0
10
0
0
19
0
28
0
10
% E
% Phe:
0
0
46
0
0
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
19
0
10
0
10
19
0
0
0
% I
% Lys:
0
0
0
0
0
10
0
10
0
0
0
10
0
0
0
% K
% Leu:
0
28
10
10
0
0
64
0
46
55
55
0
0
19
0
% L
% Met:
0
10
0
0
10
0
0
0
0
10
0
0
10
0
0
% M
% Asn:
10
0
10
0
0
0
0
10
0
0
10
0
0
0
19
% N
% Pro:
0
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% P
% Gln:
10
10
0
0
0
10
0
0
0
0
0
46
55
10
10
% Q
% Arg:
0
0
0
0
82
0
10
0
19
10
10
19
0
10
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
55
0
10
0
0
0
0
0
% T
% Val:
0
46
0
0
0
0
0
0
19
19
0
0
0
46
0
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _